Description
A muscarinic acetylcholine receptor antagonist (Kis = 15.8, 11.2, 12.6, 22.4, and 25.1 nM for human M1-5, respectively); reduces micturition pressure and increases bladder capacity and ICI in conscious female rats when administered at a dose of 0.01 mg/kg; reduces intermicturition pressure and prevents bladder overactivity in a rat model of spinal cord injury-induced overactive bladder